|Axion BioSystems Travel Award Winner: Congratulations Matheus Victor
Congratulations to Dr. Matheus Victor for being selected as a winner of the 2019 Koch Institute Image Award competition! The featured image is of neurons differentiated from human induced pluripotent stem cells immunostained with a neurofilamant antibody and plated on a 48-well CytoView MEA. Mat’s winning image will be on display at the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology for one year.
To learn more about the science behind this image click here.
|Axion BioSystems Travel Award Winner: Congratulations Katherine Savell
Congratulations to Katherine Savell for her recent Axion BioSystems Travel Award. Katherine presented her research on drugs of abuse at the America Society of Gene and Cell Therapy. In this study, a multiplexed CRISPR sgRNA delivery system was used to recreate a dopamine-induced gene expression program in cultured striatal neurons. Maestro MEA was integrated with this approach to identify how dopamine-regulated gene programs influence neuronal physiology and function.
To read more about Katherine's research, click here.
|In Vitro Techniques for Assessing Neurotoxicity Using Human iPSC-Derived Neuronal Models
Learn how researchers used Maestro technology to demonstrate that spontaneously active human iPSC-derived neuronal co-cultures are a promising model for in vitro neurotoxicity assessment.
Tukker A, Wijnolts F, et al. (2019). Cell Culture Techniques.
Read the full chapter here.
|Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro
Explore how Maestro MEA technology helped to create a comprehensive and efficient differentiation paradigm for hiPSCs that offers critical insights into the network activity aspects of Schizophrenia and may serve as a promising tool for modeling diseases with hippocampal vulnerability.
Sarkar A, Mei A, et al. (2018). Cell Stem Cell.
Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses
Discover how Maestro technology helped researchers use differentiated hypothalamic-like neurons (iHTNs) derived from normal and obese patients to show how these cells provide a powerful platform to study obesity and gene-environment interactions.
Rajamani U, Gross A, et al. (2018). Cell Stem Cell.
In Vitro Screening for Seizure Liability Using Microelectrode Array Technology
Discover how Maestro MEA technology makes it possible to identify seizurogenic drug effects at early stages of the development process, ensuring the development of safe candidate compounds.
Bradley JA, Luithardt HH, et al. (2018) Toxicol Sci.
|DDSSCC 2019 (May 13-15 | Crete, Greece)
Also known as the "Development of the Dopaminergic System - From Stem Cells to Circuits“ meeting, this three day show will focus on the development and function of dopamine neurons. Join Axion in Greece to learn more about how Maestro MEA can help you explore neural circuitry.
|NeuroFrance 2019 (May 22-24 | Marseille, France)
Axion's Europe Team will be attending the NeuroFrance show in Marseille this May. Stop by to see how Maestro Pro and Edge are impacting neuroscience in Europe.
|International Society for Heart Research (ISHR) (June 3-6 | Beijing, China)
Register for ISHR 2019 and join us for an international forum focusing on cutting edge research in the cardiovascular field.Come and experience how MEA technology has helped advance cardiac assays world-wide.
|World Pharma Week (WPW) (June 17-20 | Boston, MA)
Held in Boston this year, this meeting will bring together pharmaceutical decision makers from across the globe. The program covers a spectrum of preclinical research and translation across all therapeutic areas, and will include a variety of Maestro MEA research and data.
|ISSCR 2019 (June 26-29 | Los Angeles, CA | Booth 621)
In the Los Angeles area June 26-29? Come by booth 621 to see how Maestro technology is impacting the field of stem cell research and to learn more about the world's most advanced MEA systems. While at the show, don't miss the numerous posters featuring Maestro MEA data, including ours titled:
"Multiwell microelectrode array technology for the evaluation of human iPSC-derived cardiomyocyte and neuron development, optimization, and validation."
"Maturation of hiPSC-CM Function for Improved Predictivity of In Vitro CM-MEA Assays."
"Scalable Multiwell Microelectrode Array (MEA) Technology for the Evaluation of Cardiac and Neural Three-Dimensional Cell Cultures."
|Custom File Naming
In AxIS Navigator, raw files and analysis files are named based on the continuous data stream used to generate the file. However, properties such as date, duration, or investigator can also be included in the file name using macros. To name a file using macros, deselect the Auto-Name File checkbox in Experiment Setup Properties. Right-click in the file name field, select Macros, and choose a macro from the menu. A file name may be a mixture of macros and user entered text.