2019 June Axion Circuit Newsletter

Travel Award \| Publications \| Upcoming Events \| AxIS Tips	June, 2019

.... Travel Award

Axion BioSystems Travel Award Winner: Congratulations Danielle Tomasello

Congratulations to Danielle Tomasello at the Whitehead Institute for Biomedical Research, this month's Travel Award winner for her research using extracellular recordings from zebrafish larvae to shed light on neurodevelopment disorders such as autism spectrum disorder, epilepsy, attention deficit hyperactivity disorder, and more.

To read more about Danielle’s research, click here.

.... Publications

	A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity Discover how Maestro technology helped researchers develop a reproducible iPSC-derived human 3-D brain microphysiological system (BMPS) in order to investigate neuron-neuroglia function in neurotoxicology and other pathogenic mechanisms. Pamies D, Barreras P, et al. (2016). ALTEX. Read the full article here.
	Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells See how Maestro MEA technology makes it possible to use a midbrain organoid system for advanced in vitro disease modeling and therapy development. Monzel A, Smits L, et al. (2017). Stem Cell Reports. Read the full article here.
	Developing hiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays Explore how Maestro MEA technology helped to create a 3-D model that can be used like an organotypic slice culture to model human cortical development and for the physiological interrogation of developing neural circuits. Phillips A, Nestor JE, et al. (2017). Jove. Read the full article here.
	Spheroid Culture of Mammalian Olfactory Receptor Neurons: Potential Applications for a Bioelectronic Nose Learn how researchers used Maestro technology to demonstrate that the ORN spheroid culture process is a promising technique for the development of a bioelectronic nose and high-throughput odorant screening device. Kim S, Kim SY, et al. (2019). Experimental Neurobiology. Read the full chapter here.

.... Upcoming Events

	World Pharma Week (WPW) (June 17-20 \| Boston, MA \| Booth 446) Held in Boston this year, this meeting will bring together pharmaceutical decision makers from across the globe. The program covers a spectrum of preclinical research and translation across all therapeutic areas, and will include a variety of Maestro MEA research and data.
	Japanese Society of Toxicology (June 26-28 \| Tokushima, Japan) Attending the JSOT meeting this year? Stop by our sponsored talk with NeuCyte, presented by Jonathan Davila, and learn more about in vitro neurotoxicity assessments on Maestro Edge and Pro: "Building an In Vitro Phenotypic Assay Platform for Neurotoxicity Assessment with Highly Functional Human iPSC-Derived Neurons Combined with Highly Sensitive, High Throughput Multielectrode Array (MEA)."
	ISSCR 2019 (June 26-29 \| Los Angeles, CA \| Booth 621) In the Los Angeles area June 26-29? Come by booth 621 to see how Maestro technology is impacting the field of stem cell research and to learn more about the world's most advanced MEA systems. While at the show, don't miss the numerous posters featuring Maestro MEA data, including ours titled: "Multiwell Microelectrode Array Technology for the Evaluation of Human iPSC-Derived Cardiomyocyte and Neuron Development, Optimization, and Validation." "Maturation of hiPSC-CM Function for Improved Predictivity of In Vitro CM-MEA Assays." "Scalable Multiwell Microelectrode Array (MEA) Technology for the Evaluation of Cardiac and Neural Three-Dimensional Cell Cultures."
	FENS Regional Meeting (July 10-13 \| Belgrade, Serbia \| Booth 11) The Axion Europe team will be in Serbia this year promoting Maestro MEA technology at the regional FENS meeting. Come see how Maestro is impacting the world of neuroscience in Europe.

... AxIS Tips

Stimulation Studio makes electrical stimulation easy

AxIS Navigator’s Stimulation Studio has built-in cardiac and neural stimulation blocks with optimized stimulation parameters and artifact removal, making the design of electrical stimulation protocols easy. Simply drag the heart (cardiac applications) or brain (neural applications) block into the lane and specify the stimulation frequency using the Global Repeat Settings bar, select which wells/electrodes to stimulate, and press Start.

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	World Pharma Week (WPW) (June 17-20 \| Boston, MA \| Booth 446) Held in Boston this year, this meeting will bring together pharmaceutical decision makers from across the globe. The program covers a spectrum of preclinical research and translation across all therapeutic areas, and will include a variety of Maestro MEA research and data.
	Japanese Society of Toxicology (June 26-28 \| Tokushima, Japan) Attending the JSOT meeting this year? Stop by our sponsored talk with NeuCyte, presented by Jonathan Davila, and learn more about in vitro neurotoxicity assessments on Maestro Edge and Pro: "Building an In Vitro Phenotypic Assay Platform for Neurotoxicity Assessment with Highly Functional Human iPSC-Derived Neurons Combined with Highly Sensitive, High Throughput Multielectrode Array (MEA)."
	ISSCR 2019 (June 26-29 \| Los Angeles, CA \| Booth 621) In the Los Angeles area June 26-29? Come by booth 621 to see how Maestro technology is impacting the field of stem cell research and to learn more about the world's most advanced MEA systems. While at the show, don't miss the numerous posters featuring Maestro MEA data, including ours titled: "Multiwell Microelectrode Array Technology for the Evaluation of Human iPSC-Derived Cardiomyocyte and Neuron Development, Optimization, and Validation." "Maturation of hiPSC-CM Function for Improved Predictivity of In Vitro CM-MEA Assays." "Scalable Multiwell Microelectrode Array (MEA) Technology for the Evaluation of Cardiac and Neural Three-Dimensional Cell Cultures."
	FENS Regional Meeting (July 10-13 \| Belgrade, Serbia \| Booth 11) The Axion Europe team will be in Serbia this year promoting Maestro MEA technology at the regional FENS meeting. Come see how Maestro is impacting the world of neuroscience in Europe.