Axion BioSystems Travel Award Winner: Congratulations Sylmarie Davila-Montero
Congratulations to Sylmarie Davila-Montero at Michigan State University, this month's Travel Award winner for her research developing algorithms to improve the identification of neuroactive compounds using Maestro MEA data. Sylmarie demonstrated that the inclusion of temporal rather than endpoint data increased compound classification accuracy from 86% to 93%.
To read more about Sylmarie's research, click here.
Neuronal impact of patient-specific aberrant NRXN1α splicing
Learn how Axion's Maestro MEA was used to demonstrate how reduced neuronal activity in patient-derived NRXN1+/− hiPSC-neurons can be ameliorated by overexpression of individual control isoforms of the gene.
Flaherty E, Zhu S, et al. (2019). Nature Genetics.
Discover how Axion’s Maestro MEA platforms are being used to support research into neurodiseases such as Parkinsons Disease.
CAR-TCR Europe Summit (Feb 24-27 | London, UK)
Visit Axion’s booth to see how Axion’s new Maestro Z platform is being used to test the potency of T cells in real-time, label-free kill assays.
Use Stimulation Paddles for Cardiac Electrical Stimulation
Stimulation paddles are dedicated stimulation electrodes available on CytoView MEA 24, BioCircuit MEA 24 and 48, and E-Stim+ Classic MEA 48 well plates. Performing cardiac electrical stimulation with stimulation paddles is often more effective at evoking activity and capturing the entire network than stimulating through microelectrodes. In Stimulation Studio, settings for the stimulation paddle can be edited in the Pacing Properties window by double-clicking on the Cardiac Pacing Stimulation Block.
"Easy to use, great results, and promising future directions"
"Our Maestro Pro MEA has proven to be a fantastic tool in our research so far. The instrument itself is high quality and user-friendly and the software has a coherent interface that makes operating the instrument and data analysis easy to learn. The Axion team has been incredibly available and helpful whenever we hit a snag or have questions - they have even been proactive to reach out to us with information they think might be useful for our applications. We have only scratched the surface with the capabilities of the Maestro Pro in our applications and we have exciting plans of incorporating it more broadly into our research and services moving forward."
Jacquelyn Webb, Thermo Fischer Scientific
Click here to learn more about the success of Maestro Pro users.