Comparison of acute effects of neurotoxic compounds on network activity in human and rodent neural cultures
The authors generated excitatory and inhibitory hiPSC-derived neurons independently and co-cultured the neurons with primary human astrocytes. The resulting co-cultures exhibited neural activity and formed synchronized neural network activity recorded on Axion's MEA platform.
Saavedra L, Wallace K, et al. (2021). Toxicological Sciences.