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SARS-CoV-2 infects human pluripotent stem cell-derived cardiomyocytes, impairing electrical and mechanical function
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Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing
Specific genes in human induced pluripotent stem cell-derived cardiomyocytes were evaluated to determine the role in the sinoatrial node. Axion's Maestro MEA platform was used to assess the changes in cardiac beat rate.
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Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids
A compliant, multifunctional 3D electronic interface to surround a bioengineered brain organoid was developed. With a custom connection to the Maestro Pro, the authors were able to record the functional neuronal activity from the surface of the organoid.
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The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease
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Society of Toxicology Virtual (March 12-26)
Be sure to visit our virtual booth to see how Maestro research is impacting the field of toxicology and learn more about the world's most advanced MEA and impedance platform.
Innate Killer Summit (March 23-25)
Stop by our virtual booth and discover how researchers are using our Maestro Z and ZHT assay systems to track NK cell mediated cancer cell killing label-free and in real time.
In AxIS Z, the Plate Map Setup panel is used to set up Well Groups for each treatment combination, assign controls, and assign each Well Group to the plate map. Plate map templates are included to provide recommendations for Well Groups, including control types, for a specific assay or application. Plate map templates may be loaded by selecting the Load Template option from the Well Groups drop-down menu. Pre-designed templates for specific applications such as Immuno-oncology, GPCR, Cytotoxicity, and Cell Growth are provided. Templates below the horizontal line in the menu (Example Immuno-oncology, Well-by-well, etc.) provide example plate map designs that include well assignments in the Plate Map.
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Our Maestro Pro MEA has proven to be a fantastic tool in our research so far. The instrument itself is high quality and user-friendly and the software has a coherent interface that makes operating the instrument and data analysis easy to learn. The Axion team has been incredibly available and helpful whenever we hit a snag or have questions - they have even been proactive to reach out to us with information they think might be useful for our applications. We have only scratched the surface with the capabilities of the Maestro Pro in our applications and we have exciting plans of incorporating it more broadly into our research and services moving forward.
Jacquelyn Webb |
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