Publications

Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure

Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery

The Maestro Pro MEA platform was used to characterize spontaneous spiking activity in iCell GABAneurons(R) over the course of a month.

miR-29a and the PTEN–GSK3β axis are involved in aluminum-induced damage to primary hippocampal neuronal networks

News

Studying Brains on a Lab Bench 

Microelectrode array technology enables neuroscientists to investigate neural networks from the comfort of their lab bench; here, James Ross discusses its implications for understanding neurological diseasess.

Probing Models of Neurological Disease in a Dish Using Multielectrode Arrays 

Researchers are opening new doors to model and treat neurological diseases using induced pluripotent stem cell-derived neurons. See how they are being used to recapitulate diseases such as ALS and epilepsy.

Upcoming Events

World Bispecific Summit (Sept 29-Oct 1)

Discover how the Maestro Z and ZHT platforms can be used to assess immunotherapies in vitro.

Immuno Series UK (Oct 13-15)

Stop by in person or virtually and learn how the Maestro impedance platform can support your immunotherapy assays.

Cells UK (Oct 28-29)

Discover how the Maestro systems allow you to capture the functionality of your cells label-free and in real time.

AxIS Tips

The Endpoint drop-down selects the endpoint plotted by the Impedance Map and Endpoint Plot. Endpoints are calculated for each replicate.  Individual well values are displayed on the Impedance Map; and then averaged across replicate wells for the Endpoint Plot. The following endpoints are available:

• At Cursor – Impedance value at the Endpoint cursor time point.
• Maximum – Maximum impedance value between the two cursors, Endpoint Start and Endpoint End.
• Minimum – Minimum impedance value between the two cursors, Endpoint Start and Endpoint End.
• Area Under The Curve – Net area under the impedance curve between the Endpoint Start and Endpoint End cursors.
• Kill Time 50 – The time from the Endpoint Start Cursor (e.g. the dosing time) to the point of 50% cytolysis.

Customer Review

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