.... Travel Award
 

Axion BioSystems Travel Award Winner: Congratulations Xioafeng Ma 

 
Congratulations to Xioafeng Ma at Washington University St. Louis School of Medicine, this month's Travel Award winner for his research on the electrical activity of smooth uterine muscle in mice using Maestro MEA technology. Using Maestro, Xiaofeng was able to demonstrate that mouse uterine smooth muscle has different electrophysiology properties during different stages of the estrous cycle.
 
To read more about Xioafeng's research, click here
.... Publications
Translational Psych Cover Setd5 Haploinsufficiency Alters Neuronal Network Connectivity and Leads to Autistic-Like Behaviors in Mice

Discover how Maestro technology helped researchers to determine the mechanism by which a gene linked to intellectual disability (ID) and autism-spectrum disorder (ASD) causes decreased network activity and synchronicity in vitro

Moore S, Seidman J, et al. (2019). Translational Psychiatry.

Read full article here

Nature Journal Cover ALS-Implicated Protein TDP-43 Sustains Levels of STMN2, A Mediator of Motor Neuron Growth and Repair

Explore how Maestro technology was used to help researchers propose that restoring STMN2 expression warrants examination as a therapeutic drug strategy for ALS.
 
Klim J, Williams L, et al. (2019). Nature Neuroscience.
 
Read the full article here.
Screening for Neurotoxicity with Microelectrode Array

See how Maestro technology helped researchers develop a reliable, high-throughput, in vitro screening tool to identify chemical entities that cause neurotoxic and seizurogenic effects.

Bradley J, Strock C. (2019). Current Protocols in Toxicology.

Read full article here.

Assessing Seizure Liability Using Multi-Electrode Arrays (MEA)

Read about how researchers utilized Maestro technology to demonstrate that MEA, in conjunction with rat hippocampal brain slices and rat embryonic hippocampal neurons, may be useful as an early, predictive in vitro assay for seizure liability. 

Fan J, Thalody G, et al. (2019). Toxicology In Vitro.

Read full article here.

Carrier-Free Nanoparticles of Cathepsin B-Cleavable Peptide-Conjugated Doxorubicin Prodrug for Cancer Targeting Therapy

Follow researchers as they use Maestro technology to explore cancer nanomedicine techniques involving nanoparticle-based delivery systems, and attempt to solve the unavoidable problems that current nanomedicine practices face.
 
Shim MK, Park J, et al. (2019). Journal of Controlled Release. 
 
Read the full article here.
.... Upcoming Events
SOT Annual Meeting SOT2019 (March 10-14 | Baltimore, MD | Booth 3747)

Come by booth 3747 to see how Maestro research is impacting the field of toxicology and to learn more about the world's most advanced MEA systems.

Join us for our cohosted session with Lonza titled:

Refining the use of Microelectrode Array Technology: Lessons Learned from the NeuTox Pilot Study for Neurotoxicology and Safety Pharmacology Assessment (Mon Mar 11 | 4:30pm - 5:30pm | CC Room 338)

This year's SOT program is packed with Maestro research.  Click here for the complete list.

NIH Event NIH Cardiovascular Bioengineering (CVBE) Symposium (March 1-2 | Sydney, AUS)

Held for the first time in Australia and supported by the NIH, this two day meeting will bring together a faculty of internationally leading scientists from North America, Europe, the US, Asia, and Australia. The program covers a spectrum of fundamental and translational topics related to the fields of cardiac cell therapy, cardiovascular sciences, and stem cell biology. 

Learn more about this landmark event here.

  Optogenetics Course EMBL (March 27-28 | Heidelberg, DEU)

Come join our Europe team's Marc Baeuerle and Konstantinos Gkatzis at the Optogenetics Course in Heidelberg this Spring. They'll be exploring how MEA and optogenetics go hand in hand, and how Maestro technology is advancing the field of light-controlled cellular biology.

Learn more about this event here.

 ... AxIS Tips
AxIS Tips: Drag and Drop Configurations 

Did you know that you can drag and drop processors and stream configurations from one file to another in AxIS? Simply click on the processor you would like to move, drag your cursor over the new file, and release the click to transfer that processor and any downstream ones to a different file.

Have an idea you'd like to see featured in AxIS Tips? Email us at info@axionbio.com.

 

                                                                                   

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