Axion Biosystems    


>> Multielectrode arrays for functional phenotyping of neurons from induced pluripotent stem cell models of neurodevelopmental disorders
The authors provide an overview of the history of multielectrode array (MEA) applications and suggest best practices and standards for studying neurodevelopmental disorders using induced pluripotent stem cells (iPSCs). 
McCready FP, Gordillo-Sampedro S, et al. (2022). Biology. 
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>> FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis
Scientists demonstrate that ferritin heavy chain (FTH) facilitates proliferation, eliminates mitochondrial stress, and encourages ferroptosis resistance in hepatocellular carcinoma cells (HCC) in vivo and in vitro.
Hu W, Zhou C, et al. (2021). Cancer Cell International. 
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>> Genome sequencing in a genetically elusive multi-generational long QT syndrome pedigree identifies a novel LQT2-causative deeply intronic KCNH2 variant
Learn how scientists used patient-specific induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from a multigenerational family to uncover a novel deep intronic KCNH2 variant associated with long QT syndrome.
Tobert KE, Tester DJ, et al. (2022). Heart Rhythm. 
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>> Integrated omic analyses identify pathways and transcriptomic regulators associated with chemical alterations of in vitro neural network formation
Researchers demonstrate the feasibility of a novel in vitro approach for testing different classes of neurotoxic compounds and reveal that alterations in network formation are accompanied by transcriptomic and metabolomic changes.
Marable CA, Frank CL, et al. (2021). Toxological Sciences. 
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>> The past, present and future of antiviral discovery
Axion’s Chief Technical Officer James Ross, PhD, describes how bioelectronic assays enable scientists to overcome limitations of traditional methods and accelerate drug development for COVID-19, influenza, and other viruses.
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Upcoming Events

>> Society of Toxicology
San Diego, CA / Mar 27-31

Visit our booth to see how Maestro research is impacting the field of toxicology and learn more about the world's most advanced MEA and impedance platform.

>> ISSCR 2022 Jerusalem International Symposium   Jerusalem, Israel / Mar 30-31

Join us to learn how Axion's next-generation Maestro platforms are influencing stem cell research and discovery around the world.

>> Innate Killer Summit
San Diego, CA / Mar 30-April 1

Stop by our booth and discover how researchers are using Maestro Z and ZHT assay systems to track NK cell-mediated cancer cell killing label-free and in real time.

>> Neuroimmunology Drug Development Summit Boston, MA / April 18-20

Learn how our Maestro MEA platforms are helping researchers explore complex neural-glial and interactions and examine the role of the neuroimmune system in health and disease. 

>> American Association for Cancer Research (AACR) New Orleans, LA / April 8-13

Visit our booth to learn how Axion's bioelectronic assays enable scientists to collect continuous data, revealing the full response and kinetic interactions of immune cells and cancer.  

Travel Award

>> Axion BioSystems Travel Award Winner: Congratulations Katy Hole 
Axion is proud to support Katy Hole, PhD, of the University of Bath, as she presents her exciting work entitled Overexpression of an FTLD mutant of Tau disrupts the Tau Interactome and enhances network excitability in primary cortical neurons at AD/PD 2022 in Barcelona, Spain.

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