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.... Publications

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

Researchers used the Maestro MEA to investigate neural network changes in iPSC-derived brain organoids infected with HCMV in order to model HCMV-induced neurodevelopmental defects.
Sun G, Chiuppesi F, et al. (2020). Cell Reports Medicine. 
Read the full article here. 

Drebrin Autoantibodies in Patients with Seizures and Suspected Encephalitis

Maestro MEA data showed increased spike rates and network excitability in primary hippocampal neurons exposed to anti-Drebrin autoantibodies.
Pitsch J, Kamalizade D, et al. (2020). Annals of Neurology. 
Read the full article here. 

Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase

Learn how Maestro MEA was used to clarify the role of CIRP in sinus node plasticity and heart rate regulation under stress conditions.

Xie D, Li G, et al. (2020). Circulation Research. 
Read the full article here. 

Nanopatterned Nafion Microelectrode Arrays for In Vitro Cardiac Electrophysiology

Discover how Axion's MEAs were coated in Nafion nanopatterns to enhance the cellular environment and then used for in vitro electrophysiological analysis of two types of iPSC-CMs.  
Choi JS, Smith AST, et al. (2020). Advanced Functional Materials. 
Read the full article here.
.... Upcoming Events

As current events around COVID-19 continue to evolve, a number of scientific conferences have either canceled or rescheduled their events.  Below are a selection of videos (approx 10 mins long) that will help you keep abreast of the scientific developments from the comfort of your own home.

 ...AxIS Tips
AxIS Tip Batch Process Files

Batch process files to save time and ensure consistent analysis

Batch processing allows for multiple files to be analyzed using identical analysis settings. In AxIS Navigator, select File > New Batch Process… In the Edit Batch Process Settings window, click Add and select the desired .raw files. Select the analysis window using the Segment Type menu. Once settings have been applied, the batch process will appear in the Streams window. Analysis configurations may be applied to the batch process in the same manner as a single file, and all files in the batch process will be processed according to the stream configuration. Click the Start Batch Process button to begin analysis.

 ... Customer Review

"Easy to use, great support"

"The Lumos is a powerful system that is easy to use. The software is intuitive. The support team is very responsive to any questions I have about using the device.

Kristen Cotton, Shirley Ryan AbilityLab

Click here to learn more about the success of Lumos users.


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