Investigation into the Role of ERK in Tyrosine Kinase Inhibitor-Induced Neuropathy
Peripheral neuropathy is a common side effect of chemotherapy. The authors create an in vitro neuropathy assay screening extracellular signaling of small molecules. Evaluation of hiPSC-derived peripheral neuronal electrophysiology was conducted on the Maestro platform.
Belair DG, Sudak K, et al. (2021). Toxicological Sciences