Recreating irregular heart beats with patient cells and gene editing

 

Log QT Coffee Break Webinar

Long QT syndrome, also referred to as LQTS, is a genetic disorder which affects the repolarization of the heart after a heartbeat. This prolonged repolarization of the heart is observed as a lengthening of the QT interval in the electrocardiogram, hence the disorders name. A long QT interval can upset the careful timing of the heartbeat and trigger dangerous heart rhythms which can result in fainting, seizures, or sudden death. In this webinar, Dr. Vincenzo Macri, STEMCELL Technologies, discusses how the stem cell culture and gene editing technologies being developed by his lab can be used to recreate these patient heart beats in a dish.